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11/02/2024 07:23:46 am

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Big Data Analysis Helps Researchers Understand Genes and How They Work

SCDA

(Photo : Simons Center for Data Analysis (SCDA)) Researchers have established how genes function together within 144 different human tissues and cell types.

A team of researchers from the Simons Center for Data Analysis (SCDA) along with major universities in the U.S. are currently using big data and computational analysis to study human genes and their relation to diseases.

With big data analysis, the researchers have established how genes function and interact within 144 different human tissues and cell types.

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The team started off by gathering and integrating large amounts of information from around thirty eight thousands genome experiments.

This information consists of data about RNA (protein) cells including data from people diagnosed with different illnesses.

By combining both computer science and statistical methods to integrate and analyze massive amounts of information, the research team were able to discover hidden data that shed new light on the intricacies of human biology.

Director of the SCDA Leslie Greengard said, "Olga and her collaborators have demonstrated that extraordinary results can be achieved by merging deep biological insight with state-of-the-art computational methods, and applying them to large-scale, noisy and heterogeneous datasets."

Deputy Director Olga Troyanskaya of genomics at the SCDA and also a professor of computer science said, "A key challenge in human biology is that genetic circuits in human tissues and cell types are very difficult to study experimentally,"

"Our approach mined these big data collections to build a map of how genetic circuits function in the podocyte cells, and in many other disease-relevant tissues and cell types." Troyanskaya added.

Big data analysis has been very helpful in many other fields such as astronomy, marine science, medicine, business and online services. A leading marine science research organization in Australia (WAMSI) recently announced its move towards big data technology to help them make use of their data.

As astronomers wait for the construction of the Square Kilometer Array radio telescope, which is expected to be ready by 2018, scientists from the University of Wisconsin-Madison in the U.S. have already begun working on new software that will help astronomers interpret millions of incoming data about the cosmos from the new telescope.

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