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12/23/2024 06:44:46 am

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Scientists Identify Genes That Determine Your Nose Shape

Image showing variation between nose shape and the specific genes responsible

(Photo : Kaustubh Adhikari, UCL) Image showing variation between nose shape and the specific genes responsible

Scientists have determined which genes that determine the appearance of one's nose. These four specific genes apparently dictate how your nose will be shaped, according to a new study.

Researchers examined the faces and analyzed the DNA of 6,000 individuals, where they determined factors such as breadth, pointiness, and other distinct characteristics. These genes are known as DCHS2, RUNX2, GLI3, and PAX1, where they are responsible for the width and pointiness of the nose. Another gene known as EDAR is discovered to influence the chin's jut.

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These genes contribute to the nose's characteristics and growth of its bone and cartilage, including the overall shape of the face. More specifically, GLI3 which triggers cartilage growth has the largest influence on the shape of the nostrils. DCHS2 on the other hand is linked to the nose's pointiness and RUNX2 modifies bone growth and the width of the nose bridge.

Participants of this new study originate from South American countries that are mixed with ethnic populations. Half of this population is European, 45 percent were Native American and five percent has African ancestry.

The team also examined the photos of the volunteers to establish 14 different attributes such as nose bridge width, nose protrusion and nose tip shape. Using 3D computer simulations, their facial features were measured as well. Genetic data was then compared to each characteristic trait for any association.

According to lead author of the study Kaustubh Adhikari of the University College London, there are only a few studies that investigated how normal facial features develop and those that examined how European features develop, which only showed a little diversity compared to this new study.

Adhikari explains that these specific genes are the ones responsible for the shape and size of individual features that have not yet been identified before. By figuring out what each gene is responsible for, this can help further research to put the pieces of an evolutionary puzzle together, beginning from Neanderthals to modern humans. 

Apart from understanding the way humans evolve through time, this can also provide new insight on how genes can greatly influence the way an individual looks, which has been crucial in forensics applications. 

This new study is published in the journal Nature Communications.

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