Amanda Knox' lawyers have put in a formal request to have Italy's court of last resorts review the young woman's appeals court conviction for the 2007 murder of British roommate Meredith Kercher.

The 26-year-old's lawyer, Luciano Ghirga, told news sources on Wednesday that the paperwork had been submitted last week to Italy's highest criminal court, Court of Cassation.

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The move comes after a Florence appeals court reinstated a lower court's murder conviction of Knox and former Italian boyfriend Raffaele Sollecito in the slaying of Kercher.

The three were studying in Perugia, Italy at the time of Kercher's death. Knox spent close to four years in an Italian jail as one of the most publicized and talked about trials was played out in Italian court.

In 2011, an appeal trial freed both Knox and Sollecito, and the young woman returned to the US shortly after.

However, after the lower court's murder conviction was reinstated in January of this year, Knox faces possible prison sentences of up to 28-1/2-years and her ex-boyfriend Sollecito a possible 25-year sentence.

Knox, who turns 27 next month, has told the press that she will never "willingly" return to Italy to appear in court.

Despite controversial evidence to the contrary, Knox has long maintained her innocence and stated that she hopes the Italian courts will once again recognize her as blameless in the murder.

The 21-year-old Kercher was stabbed multiple times and the Florence court has contended that it was Knox herself who delivered the fatal knife blow. In the 337-page document in which the court laid out the reasons for conviction, it was stated that the American student wanted to "humiliate the victim" which was why she chose to assault Kercher in such a heinous fashion.

Like his co-defendant, Sollecito has also maintained that he did not have a hand in Kercher's mysterious and brutal murder.

TagsAmanda Knox, Meredith Kercher, Italy